| Preliminary Round | 1st Qualifying Round | 2nd Qualifying Round | 3rd Qualifying Round | Play-offs | Group Stage |
| 16th Finals | 8th Finals | Quarterfinals | Semifinals | Final |
Rodada:
Jogados
1ª Rodada
18/02/2021 - Quinta
07:00
Dynamo Kyiv
1
x
1
Club Brugge
09:55
Braga
0
x
2
Roma
09:55
FC Krasnodar
2
x
3
Dinamo Zagreb
09:55
Olympiacos
4
x
2
PSV Eindhoven
09:55
Real Sociedad
0
x
4
Manchester United
09:55
Red Star Belgrade
2
x
2
Milan
09:55
Slavia Praha
0
x
0
Leicester City
09:55
Wolfsberger
1
x
4
Tottenham Hotspur
09:55
Young Boys
4
x
3
Bayer Leverkusen
12:00
Antwerp
3
x
4
Rangers
12:00
Benfica
1
x
1
Arsenal
12:00
Granada
2
x
0
Napoli
12:00
Lille
1
x
2
Ajax
12:00
Maccabi Tel Aviv
0
x
2
Shakhtar Donetsk
12:00
Molde
3
x
3
Hoffenheim
12:00
Red Bull Salzburg
0
x
2
Villarreal
2ª Rodada
24/02/2021 - Quarta
09:00
Tottenham Hotspur
4
x
0
Wolfsberger
25/02/2021 - Quinta
09:55
Ajax
2
x
1
Lille
09:55
Arsenal
3
x
2
Benfica
09:55
Hoffenheim
0
x
2
Molde
09:55
Napoli
2
x
1
Granada
09:55
Rangers
5
x
2
Antwerp
09:55
Shakhtar Donetsk
1
x
0
Maccabi Tel Aviv
09:55
Villarreal
2
x
1
Red Bull Salzburg
12:00
Bayer Leverkusen
0
x
2
Young Boys
12:00
Club Brugge
0
x
1
Dynamo Kyiv
12:00
Dinamo Zagreb
1
x
0
FC Krasnodar
12:00
Leicester City
0
x
2
Slavia Praha
12:00
Manchester United
0
x
0
Real Sociedad
12:00
Milan
1
x
1
Red Star Belgrade