| 1st Qualifying Round | 2nd Qualifying Round | 3rd Qualifying Round | Play-offs | Group Stage | Round of 16 |
| Quarterfinals | Semifinals | Final |
Rodada:
Jogados
2ª Rodada
29/09/2021 - Quarta
12:00
Red Bull Salzburg
2
x
1
Lille
12:00
Wolfsburg
1
x
1
Sevilla
3ª Rodada
19/10/2021 - Terça
09:45
Beşiktaş
1
x
4
Sporting CP
09:45
Club Brugge
1
x
5
Manchester City
12:00
Ajax
4
x
0
Borussia Dortmund
12:00
Atlético de Madrid
2
x
3
Liverpool
12:00
Internazionale
3
x
1
Sheriff
12:00
Paris Saint-Germain
3
x
2
RB Leipzig
12:00
Porto
1
x
0
Milan
12:00
Shakhtar Donetsk
0
x
5
Real Madrid
20/10/2021 - Quarta
09:45
Barcelona
1
x
0
Dynamo Kyiv
09:45
Red Bull Salzburg
3
x
1
Wolfsburg
12:00
Benfica
0
x
4
Bayern Munich
12:00
Chelsea
4
x
0
Malmö
12:00
Lille
0
x
0
Sevilla
12:00
Manchester United
3
x
2
Atalanta
12:00
Young Boys
1
x
4
Villarreal
12:00
Zenit
0
x
1
Juventus
4ª Rodada
02/11/2021 - Terça
10:45
Malmö
0
x
1
Chelsea
10:45
Wolfsburg
2
x
1
Red Bull Salzburg
13:00
Atalanta
2
x
2
Manchester United
13:00
Bayern Munich
5
x
2
Benfica
13:00
Dynamo Kyiv
0
x
1
Barcelona
13:00
Juventus
4
x
2
Zenit
13:00
Sevilla
1
x
2
Lille
13:00
Villarreal
2
x
0
Young Boys
03/11/2021 - Quarta
10:45
Milan
1
x
1
Porto
10:45
Real Madrid
2
x
1
Shakhtar Donetsk
13:00
Borussia Dortmund
1
x
3
Ajax
13:00
Liverpool
2
x
0
Atlético de Madrid