| 1st Qualifying Round | 2nd Qualifying Round | 3rd Qualifying Round | Play-offs | Group Stage | Round of 16 |
| Quarterfinals | Semifinals | Final |
Rodada:
Jogados
1ª Rodada
14/09/2021 - Terça
09:45
Sevilla
1
x
1
Red Bull Salzburg
09:45
Young Boys
2
x
1
Manchester United
12:00
Barcelona
0
x
3
Bayern Munich
12:00
Chelsea
1
x
0
Zenit
12:00
Dynamo Kyiv
0
x
0
Benfica
12:00
Lille
0
x
0
Wolfsburg
12:00
Malmö
0
x
3
Juventus
12:00
Villarreal
2
x
2
Atalanta
15/09/2021 - Quarta
09:45
Beşiktaş
1
x
2
Borussia Dortmund
09:45
Sheriff
2
x
0
Shakhtar Donetsk
12:00
Atlético de Madrid
0
x
0
Porto
12:00
Club Brugge
1
x
1
Paris Saint-Germain
12:00
Internazionale
0
x
1
Real Madrid
12:00
Liverpool
3
x
2
Milan
12:00
Manchester City
6
x
3
RB Leipzig
12:00
Sporting CP
1
x
5
Ajax
2ª Rodada
28/09/2021 - Terça
09:45
Ajax
2
x
0
Beşiktaş
09:45
Shakhtar Donetsk
0
x
0
Internazionale
12:00
Borussia Dortmund
1
x
0
Sporting CP
12:00
Milan
1
x
2
Atlético de Madrid
12:00
Paris Saint-Germain
2
x
0
Manchester City
12:00
Porto
1
x
5
Liverpool
12:00
RB Leipzig
1
x
2
Club Brugge
12:00
Real Madrid
1
x
2
Sheriff
29/09/2021 - Quarta
09:45
Atalanta
1
x
0
Young Boys
09:45
Zenit
4
x
0
Malmö
12:00
Bayern Munich
5
x
0
Dynamo Kyiv
12:00
Benfica
3
x
0
Barcelona
12:00
Juventus
1
x
0
Chelsea
12:00
Manchester United
2
x
1
Villarreal